Format:
xii, 104 Seiten, Seite xiii - xv
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Illustrationen, Diagramme
Content:
As of late, epidemiological studies have highlighted a strong association of dairy intake with lower disease risk, and similarly with an increased amount of odd-chain fatty acids (OCFA). While the OCFA also demonstrate inverse associations with disease incidence, the direct dietary sources and mode of action of the OCFA remain poorly understood. The overall aim of this thesis was to determine the impact of two main fractions of dairy, milk fat and milk protein, on OCFA levels and their influence on health outcomes under high-fat (HF) diet conditions. Both fractions represent viable sources of OCFA, as milk fats contain a significant amount of OCFA and milk proteins are high in branched chain amino acids (BCAA), namely valine (Val) and isoleucine (Ile), which can produce propionyl-CoA (Pr-CoA), a precursor for endogenous OCFA synthesis, while leucine (Leu) does not. Additionally, this project sought to clarify the specific metabolic effects of the OCFA heptadecanoic acid (C17:0). Both short-term and long-term feeding studies were ...
Note:
Dissertation Universität Potsdam 2022
Additional Edition:
Erscheint auch als Online-Ausgabe Bishop, Christopher Allen Influence of dairy intake on odd-chain fatty acids and energy metabolism Potsdam, 2022
Language:
English
Keywords:
Hochschulschrift
Author information:
Klaus, Susanne
Author information:
Weitkunat, Karolin 1988-