ISSN:
1932-6203
Content:
Using multidisciplinary treatment modalities the majority of children with cancer can be cured but we are increasingly faced with therapy-related toxicities. We studied brain morphology and neurocognitive functions in adolescent and young adult survivors of childhood acute, low and standard risk lymphoblastic leukemia (ALL), which was successfully treated with chemotherapy. We expected that intravenous and intrathecal chemotherapy administered in childhood will affect grey matter structures, including hippocampus and olfactory bulbs, areas where postnatal neurogenesis is ongoing.
In:
PLOS ONE, San Francisco, California, US : PLOS, 2006, 8(2013), Seite 78599, 1932-6203
In:
volume:8
In:
year:2013
In:
pages:78599
Language:
English
DOI:
10.1371/journal.pone.0078599
