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  • 1
    UID:
    (DE-627)80116012X
    Format: Online-Ressource (xi, 221 p) , ill
    Edition: 2nd, rev. and extended ed
    Edition: Online-Ausg.
    ISBN: 1417522569 , 9781417522569
    Series Statement: Contributions to microbiology v. 11
    Note: Includes bibliographical references and index , ""Contents""; ""Dedication in Remembrance of Andreas Scheid (1941�2001)""; ""Note of the Series Editor""; ""Preface to the Second Edition""; ""Preface to the First Edition""; ""Transmissible Spongiform Encephalopathies: The Prion Theory � Background and Basic Information""; ""Non-Virus Properties of the Scrapie Agent""; ""The Concept of Two Isoforms of the Prion Protein""; ""Basic Experiments Pro and Contra Prions""; ""The Search for a Nucleic Acid""; ""Structural Transitions of the Prion Protein as Basis for the Replication Mechanism"" , ""Infectious, Sporadic and Familial Etiology of Prion Diseases Based on the Prion Model""""Outlook""; ""Acknowledgment""; ""References""; ""Structural Biology of Prions""; ""The Primary Structure of the Prion Protein""; ""The Neurotoxic Model Peptide, PrP106�126""; ""Metal-Binding Domains of the Prion Protein""; ""Secondary Structure Analysis of the Prion Protein""; ""Tertiary Structure of the Normal Prion Protein (PrPC)""; ""Influence of Familial Mutations on the Structure of the Prion Protein""; ""Tertiary Structure of the Infectious Prion Protein (PrP TSE )"" , ""Deciphering the Structure of Infectious Prion Protein with Antibodies""""Prion Protein Folding Pathways and Their Conformational Properties""; ""Conclusion""; ""References""; ""Prion Strains and Species Barriers""; ""Prion Strains""; ""Molecular Basis of Prion Strains""; ""Species Barriers""; ""Subclinical Prion Infection""; ""Implications of Prion Disease vs. Prion Infection""; ""Re-Evaluating Prion Strains and Species Barriers""; ""Acknowledgement""; ""References""; ""Prions of Saccharomyces and Podospora""; ""Three Genetic Criteria for Prions""; ""[URE3] as a Prion of the Ure2 Protein"" , ""Structure of Ure2p""""Aggregation of Ure2p in vivo and in vitro""; ""[PSI] as a Prion of the Sup35 Protein""; ""Interaction with Other Proteins in the Cell and Influence of Chaperones""; ""Prion Variants""; ""Other Prions in Saccharomyces cerevisiae""; ""[Het-s], a Prion with a Normal Cellular Function""; ""Are in vitro Produced Filaments Infectious?""; ""Acknowledgement""; ""References""; ""Human Prion Diseases: Cause, Clinical and Diagnostic Aspects""; ""Creutzfeldt-Jakob Disease""; ""Sporadic CJD (spCJD)""; ""Epidemiology and Cause""; ""Clinical Features""; ""Diagnosis"" , ""Iatrogenic (iCJD)""""Epidemiology and Cause""; ""Clinical Features""; ""Diagnosis""; ""Variant (vCJD)""; ""Epidemiology and Cause""; ""Clinical Features""; ""Diagnosis""; ""Genetic (gCJD)""; ""Epidemiology and Cause""; ""Clinical Features""; ""Diagnosis""; ""Gerstmann-Str�ussler-Scheinker Syndrome (GSS)""; ""Epidemiology and Cause""; ""Clinical Features""; ""Diagnosis""; ""Fatal Familial Insomnia""; ""Epidemiology and Cause""; ""Clinical""; ""Diagnosis""; ""Kuru""; ""Epidemiology and Cause""; ""Clinical Features""; ""Diagnosis""; ""References"" , ""Epidemiology and Risk Factors of Transmissible Spongiform Encephalopathies in Man""
    Additional Edition: 3805576560
    Additional Edition: Print version Prions
    Language: English
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