UID:
almahu_9948196669002882
Format:
1 online resource (xiv, 440 pages) :
,
illustrations
ISBN:
3527604057
,
9783527604050
,
9783527604678
,
3527604677
,
1280519525
,
9781280519529
Content:
Asymmetric catalysis represents still one of the major challenges in modern organic chemistry. Besides the well-established asymmetric metal-complex-catalysed syntheses and biocatalysis, the use of "pure" organic catalysts turned out to be an additional efficient tool for the synthesis of chiral building blocks. In this handbook, the experienced authors from academia and industry provide the first overview of the important use of such metal-free organic catalysts in organic chemistry. With its comprehensive description of numerous reaction types, e.g., nucleophilic substitution and a.
Note:
Organocatalysis : from biomimetic concepts to powerful methods for asymmetric synthesis -- On the structure of the book, and a few general mechanistic considerations -- Nucleophilic substitution at aliphatic carbon -- Nucleophilic addition to electron-deficient C=C double bonds -- Nucleophilic addition to C=N double bonds -- Nucleophilic addition to C=O double bonds -- Nucleophilic addition to unsaturated nitrogen -- Cycloaddition reactions -- Protonation of enolates and tautomerization of enols -- Oxidation -- Reduction of carbonyl compounds -- Kinetic resolution of racemic alcohols and amines -- Desymmetrization and kinetic resolution of anhydrides, desymmetrization of meso-epoxides and other prochiral substrates -- Large-scale applications of organocatalysis.
Additional Edition:
Print version: Berkessel, Albrecht. Asymmetric organocatalysis. Weinheim ; [Great Britain] : Wiley-VCH, ©2005 ISBN 3527305173
Language:
English
Keywords:
Electronic books.
