UID:
almahu_9948196894702882
Umfang:
1 online resource (xxii, 814 pages) :
,
illustrations (some color)
ISBN:
9780470145883
,
0470145889
,
9780470145890
,
0470145897
Inhalt:
In silico modeling for toxicology provides effective pre-screening for chemicals in pharmaceutical discovery and the environment. This work discusses the validation of such models for regulatory purposes, the validation criteria, and other requirements for regulatory acceptance. It also looks at QSAR models, environmental modeling, among others.
Anmerkung:
COMPUTATIONAL TOXICOLOGY; CONTENTS; SERIES INTRODUCTION; PREFACE; ACKNOWLEDGMENTS; CONTRIBUTORS; PART I INTRODUCTION TO TOXICOLOGY METHODS; 1 An Introduction to Toxicology and Its Methodologies; 2 In vitro Toxicology: Bringing the In silico and In vivo Worlds Closer; 3 Physiologically Based Pharmacokinetic and Pharmacodynamic Modeling; 4 Species Differences in Receptor-Mediated Gene Regulation; 5 Toxicogenomics and Systems Toxicology; PART II COMPUTATIONAL METHODS; 6 Toxicoinformatics: An Introduction.
Weitere Ausg.:
Print version: Computational toxicology. Hoboken, N.J. : Wiley-Interscience, ©2007 ISBN 9780470049624
Weitere Ausg.:
ISBN 0470049626
Sprache:
Englisch
Fachgebiete:
Chemie/Pharmazie
Schlagwort(e):
Electronic books.
DOI:
10.1002/9780470145890
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9780470145890
