UID:
almahu_9949641975902882
Format:
1 online resource
ISBN:
1003817718
,
9781003817710
,
9781003303282
,
1003303285
,
9781003817659
,
1003817653
Series Statement:
QSAR in environmental and health sciences
Content:
Matrix metalloproteinases (MMPs) have been established as promising biomolecular targets for novel drug design and discovery against numerous major disease conditions including various cancers, cardiovascular, neurodegenerative, inflammatory diseases, and more. This book covers various modern molecular modeling methodologies particularly related to MMP inhibitors. Included in the text are descriptions of ligand-based drug designing and structure-based drug designing modeling strategies for designing potential and target specific or selective MMPIs. This book will benefit those who are looking for an in-depth text on the design and discovery processes of novel and selective MMPIs. Features Describes modeling strategies applied to MMPs Elaborates on the designing strategies of MMPs specifically Includes in-depth analyses of related case studies Acts as a guide for medicinal chemists, not only from pharmaceutical industries, but also from academia Covers various modern molecular modeling methodologies, particularly related to MMPIs
Language:
English
DOI:
10.1201/9781003303282
URL:
https://www.taylorfrancis.com/books/9781003303282