Kooperativer Bibliotheksverbund

UID:

Format: 1 online resource (505 p.)

Edition: 1st ed.

ISBN: 1-281-17220-0 , 9786611172206 , 0-08-055759-7

Content: The science underpinning avian immunology is crucial to understanding basic immunological principles. The exceptional features of the avian immune system and different strategies birds have adopted can provide important evolutionary insights. This book provides the most complete picture of the avian immune system so far. The world-wide importance of poultry protein for the human diet, the threat of an avian influenza pandemic and heavy reliance on vaccination to protect commercial flocks world-wide demonstrates the need to review the important practical lessons in disease control presented her

Note: Description based upon print version of record. , Front Cover; Avian Immunology; Copyright Page; Contents; Foreword; Acknowledgements; List of Contributors; Chapter 1 The Importance of the Avian Immune System and its Unique Features; INTRODUCTION; THE CONTRIBUTION FROM AVIAN LYMPHOCYTES; THE CONTRIBUTION OF THE BURSA OF FABRICIUS; THE CONTRIBUTION OF THE CHICKEN MHC; THE CONTRIBUTIONS TO VACCINOLOGY; CONCLUSIONS; REFERENCES; Chapter 2 Structure of the Avian Lymphoid System; INTRODUCTION; THE GC OF PERIPHERAL LYMPHOID ORGANS; THYMUS; BURSA OF FABRICIUS; SPLEEN; GUT-ASSOCIATED LYMPHOID TISSUES , HARDERIAN AND CONJUNCTIVAL-ASSOCIATED LYMPHOID TISSUESMURAL LYMPH NODE; ECTOPIC LYMPHOID TISSUE AND THE PINEAL GLAND; BONE MARROW; BLOOD; REFERENCES; Chapter 3 Development of the Avian Immune System; INTRODUCTION; ORIGINS AND MIGRATION ROUTES OF HAEMATOPOIETIC CELLS USING QUAIL/CHICK COMPLEMENTARY CHIMAERAS; AORTIC CLUSTERS AS THE INTRA-EMBRYONIC SOURCE OF DEFINITIVE HAEMATOPOIESIS; FORMATION OF THE AORTA: A DORSAL ANGIOBLASTIC LINEAGE AND A VENTRAL HAEMANGIOBLASTIC LINEAGE; THE AVIAN THYMUS AND T CELL DEVELOPMENT; THE BURSA OF FABRICIUS, B CELL ONTOGENY AND IMMUNOGLOBULINS , LYMPHOCYTE-DIFFERENTIATING HORMONESDEVELOPMENT OF THE IMMUNE RESPONSES; CONCLUSIONS; ACKNOWLEDGEMENTS; REFERENCES; Chapter 4 B Cells, the Bursa of Fabricius and the Generation of Antibody Repertoires; INTRODUCTION; GENERATION OF AVIAN ANTIBODY REPERTOIRES; GENERATION OF IG MOLECULES BY V(D)J RECOMBINATION; GENERATION OF IG DIVERSITY BY SOMATIC GENE CONVERSION; DEVELOPMENT OF AVIAN B CELLS; REFERENCES; Chapter 5 Avian T Cells: Antigen Recognition and Lineages; INTRODUCTION; TCR STRUCTURE AND LINEAGES; CD3 SIGNALLING COMPLEX; CD4 AND CD8; COSTIMULATORY MOLECULES; T CELL LINEAGES; PERSPECTIVES , REFERENCESChapter 6 Structure and Evolution of Avian Immunoglobulins; INTRODUCTION; AVIAN IMMUNOGLOBULINS; AVIAN ANTIBODY RESPONSES; IMMUNOGLOBULIN HALF-LIFE; NATURAL ANTIBODIES; MATERNAL ANTIBODIES; THE CHICKEN EGG AS A SOURCE OF ANTIBODIES; REFERENCES; Chapter 7 Avian Innate Immune Responses; INTRODUCTION; CONSTITUTIVE BARRIERS; ACTIVE RESPONSES (CHEMICAL); ANTIMICROBIAL PEPTIDES; THE COMPLEMENT SYSTEM; CELLS OF THE INNATE IMMUNE SYSTEM; PATTERN RECOGNITION RECEPTORS; SUMMARY; ACKNOWLEDGEMENTS; REFERENCES; Chapter 8 The Avian MHC; INTRODUCTION , THE CLASSICAL CHICKEN MHC IS SMALL, SIMPLE AND REARRANGEDTHE CLASSICAL CHICKEN MHC ENCODES SINGLE DOMINANTLY-EXPRESSED CLASSICAL CLASS I AND II MOLECULES; THE PROPERTIES OF THE SINGLE DOMINANTLY-EXPRESSED CLASS I AND II MOLECULES CAN EXPLAIN RESPONSES TO PATHOGENS AND VACCINES; THE SINGLE DOMINANTLY-EXPRESSED CLASS I MOLECULE IS DUE TO CO-EVOLUTION WITH TAP AND TAPASIN; THE CHICKEN MHC GIVES INSIGHTS INTO THE PRIMORDIAL MHC AND THE SUBSEQUENT EVOLUTION OF THE MHC; REFERENCES; Chapter 9 Avian Antigen Presenting Cells; INTRODUCTION; DEVELOPMENT OF MYELOID CELLS , SOURCES FOR AVIAN MACROPHAGES AND DC , English

Additional Edition: ISBN 0-12-370634-3

Language: English