UID:
edocfu_9959327406502883
Format:
1 online resource (xviii, 385 pages) :
,
illustrations, portraits
ISBN:
9783527651085
,
352765108X
,
9783527651115
,
352765111X
,
9781299241206
,
1299241204
Content:
"Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs. The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtually every researcher in drug discovery and pharmaceutical chemistry, and--together with the previous volumes--constitutes the first systematic approach to drug analogue development"--Publisher's website.
Note:
General Aspects. Pioneer and Analogue Drugs /
,
Competition in the Pharmaceutical Drug Development /
,
Metabolic Stability and Analogue-Based Drug Discovery /
,
Use of Macrocycles in Drug Design Exemplified with Ulimorelin, a Potential Ghrelin Agonist for Gastrointestinal Motility Disorders /
,
Drug Classes. The Discovery of Anticancer Drugs Targeting Epigenetic Enzymes /
,
Thienopyridyl and Direct-Acting P2Y Receptor Antagonist Antiplatelet Drugs /
,
Selective Estrogen Receptor Modulators /
,
Discovery of Nonpeptide Vasopressin V2 Receptor Antagonists /
,
The Development of Cysteinyl Leukotriene Receptor Antagonists /
,
Case Studies. The Discovery of Dabigatran Etexilate /
,
The Discovery of Citalopram and Its Refinement to Escitalopram /
,
Tapentadol : From Morphine and Tramadol to the Discovery of Tapentadol /
,
Novel Taxanes: Cabazitaxel Case Study /
,
Discovery of Boceprevir and Narlaprevir: A Case Study for Role of Structure-Based Drug Design /
,
A New-Generation Uric Acid Production Inhibitor: Febuxostat /
Additional Edition:
Print version: Analogue-based drug discovery III. Weinheim : Wiley-VCH, [2013] ISBN 9783527330737
Language:
English
Keywords:
Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9783527651085
