UID:
edocfu_9959327581002883
Format:
1 online resource (2 volumes (xxi, 717 pages)) :
,
illustrations (some color)
ISBN:
9783527699131
,
3527699139
,
9783527699124
,
3527699120
,
9783527699148
,
3527699147
,
9783527699155
,
3527699155
Series Statement:
Methods and principles in medicinal chemistry ; v. 71a-71b
Uniform Title:
Protein therapeutics (Wiley-VCH)
Content:
In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.
Note:
Volume I -- Volume II.
Additional Edition:
Print version: Protein therapeutics. Weinheim, Germany : Wiley-VCH, [2017] ISBN 3527340866
Additional Edition:
ISBN 9783527340866
Language:
English
Keywords:
Electronic books.
DOI:
10.1002/9783527699124
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9783527699124
