Tetrahedron, 25 November 2012, Vol.68(47), pp.9694-9700
Nine new steroids, sclerosteroids A–I ( , , , – ), along with 18 known metabolites ( – , , – ), were isolated from the soft coral These structures were elucidated on the basis of detailed spectroscopic analysis. The absolute configurations of sugar moieties in steroidal glycosides – were determined by HPLC analysis of the -tolylthiocarbamate derivatives of the liberated sugars from hydrolysis of these steroidal giycosides. Cytotoxic and anti-inflammatory activities of these compounds were measured in vitro.
Scleronephthya Gracillimum ; Sclerosteroids ; O-Tolylthiocarbamate ; Cytotoxic Activity ; Anti-Inflammatory Activity ; Chemistry
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