Format:
Online-Ressource (xvii, 343 p.)
,
ill. (some col.)
Edition:
2. ed.
Edition:
Online-Ausg. Amsterdam Elsevier Science & Technology 2010 Elsevier e-book collection - Neuroscience Electronic reproduction; Mode of access: World Wide Web
ISBN:
1282619578
,
9781282619579
,
9780123749512
Content:
Many who work on the cellular and molecular processes of learning and memory are tempted to throw up their hands in frustration and conclude that the problem is insoluble. Human learning and memory is likely the most highly evolved and sophisticated biological process in existence. This book represents the first step at beginning to put together the complex puzzle of the molecular basis of memory. Sweatt creates a framework of thinking about synaptic plasticity and memory at the molecular level; one which recognizes and begins to incorporate this extreme biochemical complexity into our thinking about memory. Now in its second edition this is currently the only book on the market that takes this approach. All chapters are fully revised, and four new chapters have been added. The book is adaptable for courses for senior level undergraduates and, first and second year graduate students. It will be of use to students interested in the medical professions and graduate students interested in translational aspects of basic memory research at a time when translational research is becoming a priority area for research funding agencies in the US and internationally. More than 25% new content, particularly expanding the scope to include new findings in translational research. Unique in its depth of coverage of molecular and cellular mechanisms Extensive cross-referencing to Comprehensive Learning and Memory Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples
Content:
Many who work on the cellular and molecular processes of learning and memory are tempted to throw up their hands in frustration and conclude that the problem is insoluble. Human learning and memory is likely the most highly evolved and sophisticated biological process in existence. This book represents the first step at beginning to put together the complex puzzle of the molecular basis of memory. Sweatt creates a framework of thinking about synaptic plasticity and memory at the molecular level; one which recognizes and begins to incorporate this extreme biochemical complexity into our thinking about memory. Now in its second edition this is currently the only book on the market that takes this approach. All chapters are fully revised, and four new chapters have been added. The book is adaptable for courses for senior level undergraduates and, first and second year graduate students. It will be of use to students interested in the medical professions and graduate students interested in translational aspects of basic memory research at a time when translational research is becoming a priority area for research funding agencies in the US and internationally. More than 25% new content, particularly expanding the scope to include new findings in translational research. Unique in its depth of coverage of molecular and cellular mechanisms Extensive cross-referencing to Comprehensive Learning and Memory Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples
Note:
Includes index
,
Front Cover; Mechanisms of Memory; Copyright Page; Contents; Foreword to First Edition; Preface to First Edition; Preface to Second Edition; Acknowledgements; Chapter 1. Introduction: The Basics of Psychological Learning and Memory Theory; I. Introduction; A. Categories of Learning and Memory; B. Memory Exhibits Long-Term and Short-Term Forms; II. Short-Term Memory; A. Sensory Memory and Short-Term Storage; B. Working Memory; C. The Prefrontal Cortex and Working Memory; D. Reverberating Circuit Mechanisms Contrast with Molecular Storage Mechanisms for Long-Term Memory
,
III. Unconscious LearningA. Simple Forms of Learning; B. Unconscious Learning and Unconscious Recall; C. Unconscious Learning and Subject to Conscious Recall; D. Operant Conditioning; E. Currently Popular Associative Learning Paradigms; IV. Conscious Learning-Subject to Conscious and Unconscious Recall; A. Declarative Learning; B. Spatial Learning; V. Summary; Further Reading; Journal Club Articles; References; Chapter 2. Studies of Human Learning and Memory; I. Introduction-Historical Precedents with Studies of Human Subjects; A. Amnesias; B. Memory Consolidation
,
II. The Hippocampus in Human Declarative, Episodic, and Spatial MemoryA. Anatomy of the Hippocampal Formation; B. Lesion Studies in Human Memory Formation; C. Imaging Studies; III. Motor Learning; A. Anatomy; B. Habits; C. Stereotyped Movements; D. Sequence Learning; IV. Prodigious Memory; A. Mnemonists; B. Savant Syndrome; C. You are a Prodigy; V. Summary; Further Reading; Journal Club Articles; References; Chapter 3. Non-Associative Learning and Memory; I. Introduction-The Rapid Turnover of Biomolecules; II. Short-Term, Long-Term, and Ultralong-Term Forms of Learning
,
III. Use of Invertebrate Preparations to Study Simple Forms of LearningA. The Cellular Basis of Synaptic Facilitation in Aplysia; IV. Short-Term Facilitation in Aplysia is Mediated by Changes in the Levels of Intracellular Second Messengers; V. Long-Term Facilitation in Aplysia Involves Altered Gene Expression and Persistent Protein Kinase Activation-A Second Category of Reaction; VI. Long-Term Synaptic Facilitation in Aplysia Involves Changes in Gene Expression and Resulting Anatomical Changes; VII. Attributes of Chemical Reactions Mediating Memory; VIII. Sensitization in Mammals
,
IX. Summary-A General Biochemical Model for MemoryFurther Reading; Journal Club Articles; References; Chapter 4. Rodent Behavioral Learning and Memory Models; I. Introduction; II. Behavioral Assessments in Rodents; A. Assessing General Activity and Sensory Perception; B. Fear Conditioning; C. Avoidance Conditioning; D. Eye-Blink Conditioning; E. Simple Maze Learning; F. Spatial Learning; G. Taste Learning; H. Novel Object Recognition; I. Studying Memory Reconsolidation Using a Fear Conditioning Protocol; III. Modern Experimental Uses of Rodent Behavioral Models
,
A. The Four Basic Types of Experiments
,
Electronic reproduction; Mode of access: World Wide Web
Additional Edition:
ISBN 9780080959191
Additional Edition:
ISBN 0123749514
Additional Edition:
ISBN 9780123749512
Additional Edition:
Erscheint auch als Druck-Ausgabe Mechanisms of Memory
Language:
English
Subjects:
Psychology
Keywords:
Gedächtnis
;
Neurophysiologie
URL:
Volltext
(An electronic book accessible through the World Wide Web; click for information)
