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  • Hayes, Daniel F.  (3)
  • Kelloff, Gary J.
  • Mikulski, Stanislaw
  • 1
    UID:
    gbv_1646271068
    Umfang: Online-Ressource (XLI, 2005 p, digital)
    ISBN: 9780387310565
    Serie: SpringerLink
    Inhalt: Oncology: Evidence-Based Approach is a textbook designed to reflect the principles and current practice of oncology with contributors from the fields of medical, surgical, and radiation oncology. The textbook will incorporate an evidence-based approach, enabling the reader to make decisions on the basis of concrete data. Sections on solid tumors, hematologic malignancies and the practice of oncology address the natural history and therapy for the full spectrum of neoplastic diseases in the adult. Further sections present fundamentals of supportive care of the cancer patient, the management of oncologic emergencies and acute toxicities of therapy, as well as care of metastatic disease and the terminally-ill patient. Breaking new ground, the textbook features thoughtful, in-depth sections on cancer prevention and control, cancer surviorship, the economics of cancer care, and cancer informatics. Cancer imaging is covered with an organ system-based approach, with an additional chapter on the especially intriguing potential of PET. Furthermore, a comprehensive section on translational basic science reviews the fundamentals of molecular biology, the cell cycle and signal transduction, carcinogenesis, cancer genetics, the biology of invations and metastasis, and tumor immunology.
    Anmerkung: Includes bibliographical references and index , Front Matter; Evidence-Based Approach to Oncology; Principles of Chemotherapy; Principles of Radiation Oncology; Principles of Surgical Therapy in Oncology; Principles of Targeted and Biological Therapies; Biologic Principles of Hematopoietic Stem Cell Transplantation; Evaluation of Tumor Markers: An Evidence-Based Guide for Determination of Clinical Utility; Design and Analysis of Oncology Clinical Trials; Ethics of Clinical Oncology Research; Informatics Infrastructure for Evidence-Based Cancer Medicine; Economics of Cancer Care; Principles of Screening for Cancer; Patient Decision Making , Establishing an Interdisciplinary Oncology TeamPrinciples of Complementary and Alternative Medicine for Cancer; Fundamental Aspects of the Cell Cycle and Signal Transduction; Viral Carcinogenesis; Environmental Carcinogenesis; Cancer Metastasis; Tumor Immunology and Immunotherapy; Technologies in Molecular Biology: Diagnostic Applications; Cancer Epidemiology; Evidence-Based Cancer Prevention Research: A Multidisciplinary Perspective on Cancer Prevention Trials; Screening; Genetic Screening and Counseling for High-Risk Populations; Behavior Modification; Central Nervous System Imaging , Breast ImagingImaging of Thoracic Malignancies; Imaging of Gastrointestinal Stromal Tumor; Genitourinary Imaging; Musculoskeletal Imaging; Positron Emission Tomography and Cancer; Central Nervous System Tumors; Eye, Orbit, and Adnexal Structures; Head and Neck Cancer; Lung Cancer; Therapy for Malignant Pleural Mesothelioma; Mediastinum; Esophageal Cancer; Stomach; Colon, Rectal, and Anal Cancer Management; Adenocarcinoma and Other Small Intestinal Malignancies; Cancer of the Liver and Bile Ducts; An Evidence-Based Approach to the Management of Pancreatic Cancer; Renal Cell Cancer , Ureter, Bladder, Penis, and UrethraProstate Cancer; Testis Cancer; Cervix, Vulva, and Vagina; Gestational Trophoblastic Neoplasia; Ovarian Cancer; Uterine Malignancies; Evidence-Based Management of Breast Cancer; Thyroid and Parathyroid; Tumors of the Endocrine System; Sarcomas of Bone; Soft Tissue Sarcoma; Cutaneous Melanoma; Nonmelanoma Cutaneous Malignancies; Cancer of Unknown Primary Site; Solid Tumors of Childhood; Acute Myeloid Leukemia and the Myelodysplastic Syndromes; Acute Lymphoblastic Leukemia; Chronic Lymphocytic Leukemia and Related Chronic Leukemias; Chronic Myeloid Leukemia , An Evidence-Based Approach to the Management of Hodgkin's LymphomaThe Non-Hodgkin's Lymphomas; Multiple Myeloma; Superior Vena Cava Syndrome; Central Nervous System Emergencies; Metabolic Emergencies in Oncology; Surgical Emergencies; Oral Complications of Cancer Therapy; Alopecia and Cutaneous Complications of Chemotherapy; Infectious Complications of Cancer Therapy; Acute Toxicities of Therapy: Pulmonary Complications; Cardiac Complications; Neurologic Complications of Therapy; Acute Toxicities of Therapy: Urologic Complications , Issues in Vascular Access with Special Emphasis on the Cancer Patient
    Weitere Ausg.: ISBN 9780387242910
    Weitere Ausg.: Buchausg. u.d.T. Oncology New York, NY : Springer, 2006 ISBN 0387242910
    Weitere Ausg.: ISBN 9780387242910
    Sprache: Englisch
    Fachgebiete: Medizin
    RVK:
    Schlagwort(e): Onkologie ; Evidenz-basierte Medizin ; Onkologie ; Evidenz-basierte Medizin
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Buch
    Buch
    Berlin [u.a.] : Ullstein Medical
    UID:
    kobvindex_ZLB12386265
    Umfang: 153 Seiten , Ill., graph. Darst. , 29 cm
    Ausgabe: 1
    ISBN: 3861260913
    Sprache: Deutsch
    Schlagwort(e): Brustkrebs ; Atlas ; Atlas ; Atlas
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Online-Ressource
    Online-Ressource
    Totowa, NJ :Humana Press :
    UID:
    almahu_9949419452302882
    Umfang: XII, 342 p. 22 illus. , online resource.
    Ausgabe: 1st ed. 2006.
    ISBN: 9781592599158
    Serie: Cancer Drug Discovery and Development,
    Inhalt: It is now well recognized that individualized cancer treatment planning, based on tumor characteristics specific to an individual's cancer, makes it easier to select those most likely to benefit from toxic cancer therapies and to avoid treating those least likely to benefit. In Biomarkers in Breast Cancer: Molecular Diagnostics for Predicting and Monitoring Therapeutic Effect, expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers, as well as examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines to the validation of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers. Authoritative and cutting-edge, Biomarkers in Breast Cancer: Molecular Diagnostics for Predicting and Monitoring Therapeutic Effect offers laboratory investigators developing new tumor markers, clinical investigators testing them, and clinicians using them an up-to-date understanding of both the prognostic/predictive indicators and the novel molecular-targeted therapies suitable for individualizing breast cancer therapy.
    Anmerkung: General Topics -- Guidelines for the Design of Clinical Studies for the Development and Validation of Therapeutically Relevant Biomarkers and Biomarker-Based Classification Systems -- Analytical Aspects of Biomarker Immunoassays in Cancer Research -- Tissue Microarrays -- Assays for Gene Expression and Post-Translational Protein Abnormalities -- Gene Expression Profiling with DNA Microarrays -- Assays for DNA Abnormalities -- Assays for Gene Amplification -- Tissue Predictive Biomakers -- Cell Kinetics -- Urokinase-Type Plasminogen Activator and PAI-1 -- Predictive Value of c--erb-B2 for Endocrine Therapy and Chemotherapy in Breast Cancer -- erb-B2 as a Therapeutic Target -- The Epidermal Growth Factor Receptor Pathway as a Selective Molecular-Targeted Treatment in Human Breast Cancer -- p53 as a Prognostic and Predictive Indicator -- Predictive Biomarkers in Body Fluids -- Occult Metastatic Cells in Breast Cancer Patients -- Circulating HER2/neu -- Circulating Vascular Endothelial Growth Factor -- Detection of Early Tumor Dissemination in Patients With Breast Cancer -- Future Directions -- New Technologies/New Markers/New Challenges.
    In: Springer Nature eBook
    Weitere Ausg.: Printed edition: ISBN 9781617374364
    Weitere Ausg.: Printed edition: ISBN 9781588292278
    Sprache: Englisch
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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