In:
Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, Hogrefe Publishing Group, Vol. 47, No. 2 ( 2019-03-01), p. 168-170
Abstract:
Abstract. The use of selective serotonin reuptake inhibitors (SSRIs) like citalopram in the clinical treatment of depressive symptoms in children and adolescents has become increasingly common, although application is mostly off-label. The increasing number of prescriptions is not only due to their good efficacy, but also due to their good tolerability and the comparatively low risk in cases of intoxication. However, there is discussion about the cardiac safety of overdose ingestion of citalopram. Here, we report in detail on an adolescent with depressive symptoms who used 800 mg of citalopram in order to attempt suicide. In contrast to other case reports in adults, our patient showed only mild neurological symptoms and no cardiac toxicity or symptoms of a serotonin syndrome, despite a high citalopram blood concentration measured about two hours following ingestion of citalopram (633 ng/ml; therapeutic reference range for adults 50–110 ng/ml).
Type of Medium:
Online Resource
ISSN:
1422-4917
,
1664-2880
DOI:
10.1024/1422-4917/a000613
Language:
German
Publisher:
Hogrefe Publishing Group
Publication Date:
2019
detail.hit.zdb_id:
2083294-1
SSG:
2,1
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