Format:
Online-Ressource
ISSN:
1365-3075
Content:
Abstract: New copolymers of ε-caprolactone with three hydroxy-fatty acids, 12-hydroxy stearic acid, 16-hydroxyhexadecanoic acid and ricinoleic acid, were synthesized by catalytic polyesterification. The reactions were carried out in solvent-free systems and in organic solvents as well, using tin (II) 2-ethylhexanoate as catalyst, at different temperatures and molar ratios of the comonomers. Cyclic and linear polymeric products with medium molar weight of about 2000 Da have been synthesized and their chemical structures were confirmed by FT-IR, NMR and MALDI-TOF MS analysis. The synthesis parameters were optimized and the ε-caprolactone/hydroxy acid molar ratio was set as 5:1, according to mass spectrometry results. The biodegradability of the newly synthesized polymers was studied in the presence of Candida antarctica B lipase in phosphate buffer solutions (pH=7.4), at 37°C. The weight-loss profile emphasized the degradation of the 16-hydroxyhexadecanoic acid based polymer samples at more than 50% of their initial weight in 18 days of incubation in the presence of the lipase. The composition of the degradation products was assessed using the GC-MS technique and displayed residues of the comonomers moieties.
In:
volume:88
In:
number:12
In:
year:2016
In:
pages:1191-1201
In:
extent:11
In:
Pure and applied chemistry, Berlin : de @Gruyter, 1960-, 88, Heft 12 (2016), 1191-1201 (gesamt 11), 1365-3075
Language:
English
DOI:
10.1515/pac-2016-0920
URN:
urn:nbn:de:101:1-2024030513454371077597
URL:
https://doi.org/10.1515/pac-2016-0920
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2024030513454371077597
URL:
https://d-nb.info/1322581045/34
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