Format:
16
ISSN:
1432-1963
Content:
Introduction: Thymic tumors including thymomas, thymic carcinomas, and thymic carcinoid tumors are rare tumors with an incidence of 0.13/100,000. Materials and methods: A literature search was performed to identify recent findings on epidemiology, classification, and various therapeutic approaches. Results: These tumors with a wide spectrum of histologic and biologic features may be clinically unapparent for a long time or show a very aggressive behavior with local invasion and distant metastases. Surgical resection is the mainstay in stage I and II thymomas, whereas in stage III thymomas and in thymomas with pleural dissemination surgery in context of a multimodal treatment should be discussed. Thymic tumors are chemoreactive. Targeted therapies show poor results and should only be considered in the palliative situation after failure of chemotherapy. Conclusion: The new TNM (T: tumor, N: node, M: metastasis) classification of thymic tumors will help to identify the best treatment options.
Note:
Gesehen am 28.01.2019
In:
Der Pathologe, Berlin : Springer, 1994, 37(2016), 1, Seite 91-106, 1432-1963
In:
volume:37
In:
year:2016
In:
number:1
In:
pages:91-106
In:
extent:16
Language:
German
DOI:
10.1007/s00292-016-0140-5
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