In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 3 ( 2021-3-1), p. e0247522-
Abstract:
A large body of evidence suggests that self-management interventions (SMIs) may improve outcomes in chronic obstructive pulmonary disease (COPD). However, accurate comparisons of the relative effectiveness of SMIs are challenging, partly due to heterogeneity of outcomes across trials and uncertainty about the importance of these outcomes for patients. We aimed to develop a core set of patient-relevant outcomes (COS) for SMIs trials to enhance comparability of interventions and ensure person-centred care. Methods We undertook an innovative approach consisting of four interlinked stages: i) Development of an initial catalogue of outcomes from previous EU-funded projects and/or published studies, ii) Scoping review of reviews on patients and caregivers’ perspectives to identify outcomes of interest, iii) Two-round Delphi online survey with patients and patient representatives to rate the importance of outcomes, and iv) Face-to-face consensus workshop with patients, patient representatives, health professionals and researchers to develop the COS. Results From an initial list of 79 potential outcomes, 16 were included in the COS plus one supplementary outcome relevant to all participants. These were related to patient and caregiver knowledge/competence, self-efficacy, patient activation, self-monitoring, adherence, smoking cessation, COPD symptoms, physical activity, sleep quality, caregiver quality of life, activities of daily living, coping with the disease, participation and decision-making, emergency room visits/admissions and cost effectiveness. Conclusion The development of the COPD COS for the evaluation of SMIs will increase consistency in the measurement and reporting of outcomes across trials. It will also contribute to more personalized health care and more informed health decisions in clinical practice as patients’ preferences regarding COPD outcomes are more systematically included.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0247522
DOI:
10.1371/journal.pone.0247522.g001
DOI:
10.1371/journal.pone.0247522.g002
DOI:
10.1371/journal.pone.0247522.g003
DOI:
10.1371/journal.pone.0247522.t001
DOI:
10.1371/journal.pone.0247522.t002
DOI:
10.1371/journal.pone.0247522.t003
DOI:
10.1371/journal.pone.0247522.t004
DOI:
10.1371/journal.pone.0247522.s001
DOI:
10.1371/journal.pone.0247522.s002
DOI:
10.1371/journal.pone.0247522.s003
DOI:
10.1371/journal.pone.0247522.s004
DOI:
10.1371/journal.pone.0247522.s005
DOI:
10.1371/journal.pone.0247522.s006
DOI:
10.1371/journal.pone.0247522.r001
DOI:
10.1371/journal.pone.0247522.r002
DOI:
10.1371/journal.pone.0247522.r003
DOI:
10.1371/journal.pone.0247522.r004
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2267670-3
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