Format:
5
ISSN:
1879-0003
Content:
In order to evaluate the biomedical potential of three-dimensional chitinous scaffolds of poriferan origin, chondrocyte culturing experiments were performed. It was shown for the first time that freshly isolated chondrocytes attached well to the chitin scaffold and synthesized an extracellular matrix similar to that found in other cartilage tissue engineering constructs. Chitin scaffolds also supported deposition of a proteoglycan-rich extracellular matrix of chondrocytes seeded bioconstructs in an in vivo environment. We suggest that chitin sponge scaffolds, apart from the demonstrated biomedical applications, are highly optimized structures for use as filtering systems, templates for biomineralization as well as metallization in order to produce catalysts.
Note:
Gesehen am 02.03.2023
In:
International journal of biological macromolecules, New York, NY [u.a.] : Elsevier, 1979, 47(2010), 2 vom: Aug., Seite 141-145, 1879-0003
In:
volume:47
In:
year:2010
In:
number:2
In:
month:08
In:
pages:141-145
In:
extent:5
Additional Edition:
Erscheint auch als Druck-Ausgabe Ehrlich, Hermann, 1957 - Three-dimensional chitin-based scaffolds from Verongida sponges (Demospongiae: Porifera) 2010
Language:
English
DOI:
10.1016/j.ijbiomac.2010.05.009
URL:
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