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  • 1
    Online Resource
    Online Resource
    [Erscheinungsort nicht ermittelbar] : University of New South Wales. Clinical School - St Vincent's Hospital
    UID:
    (DE-627)1803446218
    Content: The pleiotropic functions of vitamin D, the clinical impact of deficiency and effect of supplementation have been a research focus in many specialties of ambulatory medicine. However, its prevalence in critical illness was not known. The parathyroid-vitamin D- calcium axis is the only endocrine axis that had not been previously described in critically ill patients. To study the effects of correction of deficiency, the dose, route and method of vitamin D supplementation needed investigation. Critically ill patients are heterogeneous and response to supplementation may not be consistent in all cohorts. This information is key to inform the design of a randomised controlled trial of supplementation. This thesis was a program of research that included a prospective observational study to describe serial changes in the parathyroid-vitamin D-calcium axis and the association with clinical outcomes in a sample of critically ill patients. This was followed by a randomised trial comparing two doses of intramuscular vitamin D to study the effectiveness and safety of supplementation. Subsequently, a sample of patients requiring life-sustaining extracorporeal support (ECMO) was studied to study pharmacokinetic profiles of vitamin D in patients with extreme disease severity. The observational study found marked changes in the parathyroid-vitamin D-calcium axis, which was associated with adverse outcomes. The supplementation study showed that a single intramuscular injection of cholecalciferol corrected vitamin D deficiency safely in critically ill patients. Vitamin D repletion was accompanied by a reduction in pro-inflammatory responses. The study on ECMO patients found them to be almost universally deficient in vitamin D. Supplementation by the single intramuscular dose corrected deficiency in only half these patients.Vitamin D deficiency is common in critical illness and is associated with adverse outcomes. Supplementation can be achieved effectively and safely in most patients. Groups of critically ill patients, such as those on ECMO are more susceptible to vitamin D deficiency and supplementation in this group is not easily achieved. This novel work and increasingly emerging evidence in the international literature provide a basis to inform the design of a high-quality comparative effectiveness randomised controlled trial of vitamin D supplementation in critically ill patients.
    Note: Dissertation University of New South Wales. Clinical School - St Vincent's Hospital 2018
    Language: English
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  • 2
    AV-Medium
    AV-Medium
    Show associated volumes
    UID:
    (DE-627)655958355
    Format: 23 Min
    Content: Die 9-jährige Quamer lebt mit ihrer Mutter und den jüngeren Geschwistern in der indischen Millionenstadt Hyderabad. Zeit zum Spielen hat sie nicht, und auch die Schule kann sie nicht besuchen. Sie muss zum Lebensunterhalt der Familie beitragen, indem sie Armreifen aus Glas mit Glitzersteinchen verziert. Sie wünscht sich, zur Schule gehen und rechnen lernen zu können, damit der Händler sie endlich fair bezahlen müsste.
    Note: Indien, 2006 , Dokumentarfilm , Urdu, Dt., Frz.,
    In: Filme für eine Welt, Filmfachstelle der Schweizer Hilfswerke (Bern), Kinder dieser Welt erzählen, Bern [u.a.] : Filme für eine Welt, 2009, (2009), 3
    In: year:2009
    In: number:3
    Language: Undetermined
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  • 3
    UID:
    (DE-627)721441319
    Format: graph. Darst.
    ISSN: 1477-9048
    In: International journal of business governance & ethics, Olney, Bucks. : Inderscience Enterprises, 2004, 7(2012), 1, Seite 37-62, 1477-9048
    In: volume:7
    In: year:2012
    In: number:1
    In: pages:37-62
    Language: English
    Keywords: Aufsatz in Zeitschrift
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  • 4
    Book
    Book
    Chennai : Duckbill
    UID:
    (DE-602)gbv_769828485
    Format: 77 S. , Ill.
    ISBN: 9788192594835
    Series Statement: Hole Books
    Language: English
    Keywords: Tag ; Chaos ; Mädchen ; Bewältigung ; Kinderbuch
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  • 5
    Book
    Book
    Chennai [India] : Duckbill Books
    UID:
    (DE-604)BV042136488
    Format: 77 S. , zahlr. Ill.
    Edition: 1. publ.
    ISBN: 9788192594835
    Series Statement: Hole books
    Language: English
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  • 6
    UID:
    (DE-627)1859959121
    Format: 1 Online-Ressource (45 p)
    Content: Technical standards help to drive the modern global economy. New standards directed to the so called “Internet of Things” (IoT), the “5G” suite of standards, and other next generation standardised technologies have become essential to enabling interoperability across a variety of critical industries worldwide.Standard development organizations (SDOs) are often responsible for the institution of standardised technologies through an open and consensus-based process where industry participants and other stakeholders collaborate to develop agreed upon technical specifications. While there are hundreds of significant SDOs, a few prominent Indian SDOs include the Telecommunications Standards Development Society, India (TSDSI) and the Bureau of Indian Standards (BIS).India is one of the world’s largest growing economies in the world, and a driver of technology innovation across important sectors. Reliant on critical innovation and competition, India’s economy is greatly influenced by the ability for its citizens to gain access to internationally agreed upon technical standards through equitable and predictable SEP licensing practices. Patents reward innovation, and it is important that SDOs have the ability to incorporate innovative new technologies. The challenge is to guard against potential abuse that produces a lock-in effect, when competitors select patented technology for standardisation thereby creating an inability to design around such technology.To mitigate potential anticompetitive harms, such a patent ‘hold-up’, and preserve competition, SDOs commonly adopt patent policies requiring the licencing of SEPs on specified fair, reasonable and non-discriminatory (FRAND) terms, and in exchange, the SEP holder enjoys royalties from a wider pool of market participants who require a licence from the SEP holder in order to access the relevant technical standard. The FRAND commitment – provided it is upheld – adequately addresses the interests of all SDO participants. Still, a minority of SEP holders commonly exploit ambiguities in the FRAND commitment or revoke their FRAND commitment altogether. As the Indian economy expands, the need for the Indian government to approach the encroaching and apparent discourse between SEPs and FRAND will grow. While many SDOs fail to provide clear and coherent definitions of FRAND within their policies, SEP licencing has a long history that has unveiled foundational principles underlying the FRAND commitment to ensure the system is competitive and beneficial to businesses and consumers.This paper recommends that the best course of action for the Indian government to facilitate a pro-competitive SEP licensing ecosystem for both experienced and inexperienced SEP negotiators is to shape new law and policy through a comprehensive and whole-of- government approach. To support its recommendations, this paper conducts an analysis of technical standards, case law, and important regulations and policies that influence the Indian and International SEP landscape as a justification for why this framework will alleviate current and prevent future SEP licensing abuse in India. Ultimately, this paper will provide an evidence-backed proposal for necessary policy changes in India that will create a competitive and innovative IoT economy and demonstrate India’s global leadership in pro-innovation policies
    Note: Nach Informationen von SSRN wurde die ursprüngliche Fassung des Dokuments August 9, 2023 erstellt
    Language: English
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  • 7
    Book
    Book
    Chennai : Duckbill
    UID:
    (DE-627)769828485
    Format: 77 S. , Ill.
    ISBN: 9788192594835
    Series Statement: Hole Books
    Language: English
    Keywords: Tag ; Chaos ; Mädchen ; Bewältigung ; Kinderbuch
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  • 8
    UID:
    (DE-627)720320976
    ISSN: 0972-687X
    In: Icfai University Press (Hyderabad), The IUP journal of organizational behavior, Hyderabad : IUP Publ., 2010, 11(2012), 2 vom: Apr., Seite 67-76, 0972-687X
    In: volume:11
    In: year:2012
    In: number:2
    In: month:04
    In: pages:67-76
    Language: English
    Keywords: Aufsatz in Zeitschrift
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  • 9
    UID:
    (DE-101)106605410X
    Format: Online-Ressource
    Edition: 1., Auflage
    ISBN: 9780470930960 , 0470930969
    Series Statement: Ceramic Transaction Series 221
    Note: Lizenzpflichtig
    Additional Edition: Druckausg. 9780470927168
    Language: English
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  • 10
    Online Resource
    Online Resource
    Hoboken, N.J. : John Wiley | Hoboken, NJ : John Wiley & Sons, Inc.
    UID:
    (DE-603)364882204
    Format: 1 Online-Ressource (xi, 244 Seiten) , Illustrationen.
    ISBN: 9781118511367 , 1118511360 , 9781118511350 , 1118511352 , 9781283735711 , 1283735717
    Series Statement: Ceramic transactions v. 235
    Content: "With contributed papers from the 2011 Materials Science & Technology symposia, this is a useful one-stop resource for understanding the most important issues in the advances and applications of electroceramics. Logically organized and carefully selected, the articles cover the themes of the symposia: Magnetoelectric Multiferroic Thin Films and Multilayers; Dielectric Ceramic Materials and Electronic Devices; and Multifunctional Oxide. An essential reference for government labs and academics in mechanical and chemical engineering, materials and or ceramics, and chemistry."--...
    Note: Includes bibliographical references and index
    Additional Edition: 9781118273357
    Additional Edition: 1118273354
    Language: English
    Keywords: Conference proceedings
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