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  • 1
    Online Resource
    Online Resource
    Complement in autoimmunity : a vital approach to a key component of the innate immune system (2004)
    [s.l.] : Karger
    Details
    UID:
    (DE-602)gbv_621662003
    Format: VI + 206 S.
    Edition: Online-Ressource Karger eBooks Collection 1997-2009
    ISBN: 9783318010244 , 3805576463 , 9783805576468
    Series Statement: Current directions in autoimmunity 7
    Content: Complement protein expression and activation control central aspects of the normal B cell response. Imbalances in these processes invariably lead to autoimmune disease. Complement activation causes tissue damage in a number of ways and may by itself lead to autoimmune disease. Although the use of complement activation inhibitors in the treatment of complement-mediated tissue injury and disease is largely in pre-clinical trials, the expectations that they will be of significant clinical value are high. This volume contains a series of review articles that address the role of complement in the pathogenesis of autoimmune disease and the ensuing tissue damage. Topics include structural and functional aspects of the CD19/CD21/CD81 complex, role of the complement system in the expression of systemic lupus erythematosus (SLE) and antiphospholipid antibody syndrome. Also featured is the role of complement activation in ischemia/reperfusion and autoimmune disease injury. Finally, in-depth reviews about complement activation in the development of glomerulonephritis in autoimmune disease and the function of membrane-bound complement regulatory proteins in autoimmunity are presented.Students as well as basic and clinical researchers in immunology who wish to understand the role of complement in the pathogenesis of autoimmune disease will value this comprehensive and up-to-date publication
    Note: Includes bibliographical references and indexes , ""Contents""; ""Introduction""; ""Signaling by the CD19/CD21 Complex on B Cells""; ""Complement Receptor 2 and Autoimmunity""; ""Apoptosis, Complement and Systemic Lupus Erythematosus: A Mechanistic View""; ""Role of C1q and C1q Receptors in the Pathogenesis of Systemic Lupus Erythematosus""; ""The Intricate Role of Complement Component C4 in Human Systemic Lupus Erythematosus""; ""The Role of Complement in the Antiphospholipid Syndrome""; ""Autoimmunity, Complement Activation, Tissue Injury and Reciprocal Effects""; ""Complement and Autoimmune Glomerular Diseases"" , ""Membrane Complement Regulatory Proteins in Autoimmune and Inflammatory Tissue Injury""""Author Index""; ""Subject Index""
    Additional Edition: ISBN 9783805576468
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9783805576468
    Language: English
    DOI: 10.1159/isbn.978-3-318-01024-4
    URL: Volltext
    URL: lizenzpflichtig
    URL: Volltext
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Online Access
    Open Access Request
    Stabi Berlin
    UB Potsdam
    MPI Bildungsforschung
    KOBV
  • 2
    Book
    Book
    Modern therapeutics in rheumatic diseases (2002)
    Totowa, NJ : Humana Press
    Details
    UID:
    (DE-605)HT013167782
    Format: XV, 655 S. : Ill., graph. Darst.
    ISBN: 0896039161
    Language: English
    Subjects: Medicine
    RVK:
    YC 9100
    Keywords: Rheumatismus ; Antirheumatikum ; Rheumatismus ; Therapie
    URL: Kapitel
    URL: Vorwort
    URL: Inhaltsverzeichnis
    Library Location Call Number Volume/Issue/Year Availability
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    Book
    HBZ
  • 3
    Book
    Book
    Combat medicine : basic and clinical research in military, trauma and emergency medicine (2003)
    Totowa, NJ : Humana Press
    Details
    UID:
    (DE-605)HT013762535
    Format: XI, 426 S. : Ill., graph. Darst.
    ISBN: 1588290700
    Language: English
    URL: Kapitel
    URL: Vorwort
    URL: Inhaltsverzeichnis
    Library Location Call Number Volume/Issue/Year Availability
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    Book
    HBZ
  • 4
    Book
    Book
    Complement in autoimmunity (2004)
    Basel [u.a.] : Karger
    Details
    UID:
    (DE-604)BV017648575
    Format: VI, 205 S. , Ill., graph. Darst.
    ISBN: 3805576463
    Series Statement: Current directions in autoimmunity 7
    Note: Includes bibliographical references and index.
    Language: English
    Subjects: Medicine
    RVK:
    XG 4400
    Keywords: Autoimmunität ; Komplement ; Aufsatzsammlung
    URL: Inhaltsverzeichnis
    Library Location Call Number Volume/Issue/Year Availability
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    Book
    BVB
  • 5
    Book
    Book
    Combat medicine : basic and clinical research in military, trauma, and emergency medicine (2003)
    Totowa, N.J. : Humana
    Details
    UID:
    (DE-603)112484751
    Format: XI, 426 S. , Ill., graph. Darst.
    ISBN: 1588290700 , 1592594077
    Language: English
    URL: Inhaltsverzeichnis
    Library Location Call Number Volume/Issue/Year Availability
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    Book
    HeBIS
  • 6
    Online Resource
    Online Resource
    Systemic lupus erythematosus : basic, applied and clinical aspects (2016)
    London : Academic Press, an imprint of Elsevier
    Details
    UID:
    (DE-604)BV045463870
    Format: 1 Online-Ressource (xxv, 614 Seiten)
    ISBN: 9780128020098
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-0-12-801917-7
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    BVB
  • 7
    Book
    Book
    Complement in autoimmunity (2004)
    Basel : Karger
    Details
    UID:
    (DE-101)968784674
    Format: VI, 205 S. , Ill., graph. Darst. , 25 cm
    ISBN: 9783805576468 , 3805576463
    Series Statement: Current directions in autoimmunity Vol. 7
    Note: Literaturangaben
    Additional Edition: Online-Ausg. Complement in Autoimmunity Basel : S. Karger, 2003
    Language: English
    Keywords: Autoaggressionskrankheit ; Pathogenese ; Komplement ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung
    URL: Inhaltsverzeichnis
    Library Location Call Number Volume/Issue/Year Availability
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    Book
    DNB
  • 8
    Online Resource
    Online Resource
    Systemic lupus erythematosus : basic, applied and clinical aspects (2020)
    London, United Kingdom : Academic Press is an imprint of Elsevier
    Details
    UID:
    (DE-602)b3kat_BV047049743
    Format: 1 Online-Ressource (xxix, 664 Seiten) , Illustrationen
    Edition: Second edition
    ISBN: 9780128145524
    Note: Cover -- Title -- Copyright -- Dedication -- Contents -- Contributors -- Introduction -- Introduction to the second edition -- Part I -- Epidemiology and diagnosis -- Chapter 1 -- History of systemic lupus erythematosus with an emphasis on certain recent major issues -- History of clinical observations -- The age of dermatology -- Transition of lupus erythematosus to systemic lupus erythematosus -- History of laboratory investigations -- Development of clinical tests -- History of genetics of SLE -- History of therapy in SLE with an emphasis on the use of steroids , History of classification criteria for SLE -- References -- Chapter 2 -- The patient -- Improve the interactions with your patients -- Do not make your patient wait -- Smile as you enter the patient's room -- Make a visible show of hand washing -- Shake hands -- Acknowledge and greet others in the room -- Ask open-ended questions -- Provide a mechanism for your patient to set the agenda -- Speak in nonmedical terms -- Be honest -- Learn to be empathetic -- Always examine your patient -- End the visit with, "Do you have any other concerns or questions?" -- Consulting in the hospital , Improving adherence -- Disability -- Patient education -- The lupus secrets -- References -- Chapter 3 -- A plea of a young patient to the lupus experts -- Reference -- Chapter 4 -- Epidemiology -- Introduction -- Incidence and prevalence -- Distribution according to gender -- Distribution according to age -- Distribution according to ethnic/racial group -- Distribution around the world -- Factors that affect the course of SLE -- Impact of race/ethnicity -- Impact of gender -- Mortality and survival in SLE -- References -- Chapter 5 -- Measuring disease activity -- References , Chapter 6 -- Disease development and outcome -- Historical perspective -- Clinical manifestations -- Assessment of disease activity -- Disease damage -- Patient reported outcomes -- Mortality -- Causes of death -- Treatment guidelines and quality indicators -- Conclusions -- References -- Chapter 7 -- Socioeconomic aspects of SLE -- Introduction -- Sociodemographic determinants of health in SLE -- Gender as a construct in risk and morbidity -- Race/ethnicity as a multidimensional determinant of outcomes -- Age and aging -- Income, poverty, and educational attainment
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-0-12-814551-7
    Language: English
    Keywords: Aufsatzsammlung
    DOI: 10.1016/C2017-0-01764-0
    URL: Volltext  (URL des Erstveröffentlichers)
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Online Access
    Open Access Request
    FU Berlin
    KOBV
  • 9
    Online Resource
    Online Resource
    Principles of Molecular Rheumatology (2000)
    Totowa, NJ : Humana Press
    Details
    UID:
    (DE-604)BV046144229
    Format: 1 Online-Ressource (XIII, 542 p. 57 illus)
    ISBN: 9781592590186
    Series Statement: Current Molecular Medicine 1
    Content: Rheumatic diseases are complex in nature and require for their optimal diagnosis and treatment a critical understanding of the mechanisms that lead to their tissue pathology and various clinical manifestations. In Principles of Molecular Rheumatology, George Tsokos and a panel of authoritative clinicians and researchers synthesize all the latest findings from across cell and molecular biology with the basic principles of rheumatology to create the first textbook of molecular rheumatology. These established experts describe the biochemical mechanisms by which apoptosis, cell signaling, complement, lipids, and viruses contribute to disease expression, and detail both immune and nonimmune cell function in rheumatic diseases. Their review of the major rheumatic diseases integrates the cellular, biochemical, and molecular biological mechanisms that are important in rheumatic disease pathogenesis. The authors also discuss the molecular and cellular mechanisms of action following the administration of the principal drugs used in rheumatology. Path-breaking and illuminating, Principles of Molecular Rheumatology expands the envelope of clinical understanding to reveal the biological roots underlying rheumatologic disease, as well as the nature and roles of the powerful new therapeutics now emerging for its optimal treatment
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9781617371820
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9781468496130
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9780896037731
    Language: English
    DOI: 10.1007/978-1-59259-018-6
    URL: Volltext  (URL des Erstveröffentlichers)
    Library Location Call Number Volume/Issue/Year Availability
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    Online Resource
    Online Access
    Open Access Request
    BVB
  • 10
    Book
    Book
    Combat medicine : basic and clinical research in military, trauma and emergency medicine
    Totowa, N.J. : Humana Pr.
    Details
    UID:
    (DE-605)(DE-Bo110)63029953
    Format: XI, 426 Seiten
    ISBN: 1588290700
    Language: German
    Library Location Call Number Volume/Issue/Year Availability
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    Book
    HBZ
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