Format:
1 Online-Ressource (xii, 284 pages)
,
illustrations
ISBN:
0470751673
,
9780470751671
,
0470750626
,
9780470750629
,
9780865427433
,
0865427437
Content:
1. Controlling Transcription: Shared Aims and Common Mechanisms -- 2. Transcription in Eukaryotes: The Problems of Complexity -- 3. The Nucleosome: Chromatin's Structural Unit -- 4. Histone Tails: Modifications and Epigenetic Information -- 5. Higher-Order Chromatin Structures and Nuclear Organization -- 6. Transcription in a Chromatin Environment -- 7. How the Transcription Machinery Deals with Chromatin -- 8. Chromatin Remodelling Machines -- 9. Heterochromatin -- 10. Long-Term Silencing of Gene Expression -- 11. Cellular Memory and Imprinting -- 12. Mechanisms of Dosage Compensation.
Content:
Written in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression. Many human diseases have been linked to disruption of these control processes by genetic or environmental factors, and unravelling the mechanisms by which they operate is one of the most exciting and rapidly developing areas of modern biology. Chromatin is central both to the rapid changes in gene transcription by which cells respond to changes in their environment and also to the maintenance of gene expression patterns from one cell generation to the next. This book will be an invaluable guide to undergraduate and postgraduate students in the biological sciences and all those with an interest in the medical implications of aberrant gene expression
Note:
Includes bibliographical references
,
English
Additional Edition:
0865427437
Additional Edition:
9780865427433
Additional Edition:
Erscheint auch als Druck-Ausgabe Turner, Bryan M Chromatin and gene regulation Oxford ; Malden, MA : Blackwell Science, ©2001
Language:
English
Keywords:
Chromatin
;
Genregulation
DOI:
10.1002/9780470750629
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