Format:
Online-Ressource
,
v.: digital
Edition:
Online-Ausg. Springer eBook Collection. Biomedical and Life Sciences Electronic reproduction; Available via World Wide Web
ISBN:
9781441964519
Series Statement:
Advances in Experimental Medicine and Biology 684
Content:
Immunological memory has fascinated microbiologists and immunologists for decades as one of the new frontiers to conquer to better understand the response to pathogens, cancer and vaccination. Over the past decade, attention has turned to the intrinsic properties of the memory T cells themselves, as it has become clear that the eradication of both infected cells and tumors requires T cells. This book is an attempt to capture the wave of discoveries associated with these recent studies. Its chapters represent a wide collection of topics related to memory T cells by laboratories that have invested their skills and knowledge to understand the biology and the principles upon which memory T cells are generated, maintained and expanded upon re-encounter with antigen. Ultimately, these studies are all aimed at a better understanding of the function of memory T cells in protection against disease.
Note:
Includes bibliographical references and index
,
Title page; Copyright page; DEDICATION; PREFACE; ABOUT THE EDITORS; PARTICIPANTS; Table of Contents; ACKNOWLEDGEMENTS; Chapter 1 MEMORY TH1/TH2 CELL GENERATION CONTROLLED BY SCHNURRI-2; Chapter 2 TRANSCRIPTIONAL REGULATION DURING CD8 T-CELL IMMUNE RESPONSES; Chapter 3 THE ROLE OF INTERLEUKIN-2 IN MEMORY CD8 CELL DIFFERENTIATION; Chapter 4 THE ROLE OF INFLAMMATION IN THE GENERATION AND MAINTENANCE OF MEMORY T CELLS; Chater 5 THE ROLE OF OX40 (CD134) IN T-CELL MEMORY GENERATION; Chapter 6 THE ROLE OF PRECURSOR FREQUENCY IN THE DIFFERENTIATION OF MEMORY T CELLS: MEMORY BY NUMBERS
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Chapter 7 CD8 T-CELL MEMORY DIFFERENTIATION DURING ACUTE AND CHRONIC VIRAL INFECTIONSChapter 8 LONGEVITY OF T-CELL MEMORY FOLLOWING ACUTE VIRAL INFECTION; Chapter 9 PRINCIPLES OF MEMORY CD8 T-CELLS GENERATION IN RELATION TO PROTECTIVE IMMUNITY; Chapter 10 Contents 10. MEMORY T CELLS IN RHESUS MACAQUES; Chapter 11 MEMORY T-CELL SUBSETS IN PARASITIC INFECTIONS; Chapter 12 ANTIGEN SPECIFIC MEMORY T CELLS AND THEIR PUTATIVE NEED FOR THE GENERATION OF SUSTAINED ANTI-TUMOR RESPONSES; Chapter 13 MEMORY T-CELL RESPONSES AND SURVIVAL IN HUMAN CANCER: REMEMBER TO STAY ALIVE
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Chapter 14 ANALYSIS OF VACCINE-INDUCED T CELLS IN HUMANS WITH CANCERChapter 15 MEMORY T-CELL HOMEOSTASIS AND SENESCENCE DURING AGING; INDEX;
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Memory Th1/Th2 cell generation controlled by Schnurri-2 / Toshinori Nakayama and Motoko Y. Kimura -- Transcriptional regulation during CD8 T-cell immune responses / Ivana Munitic ... [et al.] -- The role of interleukin-2 in memory CD8 cell differentiation / Onur Boyman, Jae-Ho Cho and Jonathan Sprent -- The role of inflammation in the generation and maintenance of memory T cells / Noah S. Butler and John T. Harty -- The role of OX40 (CD134) in T-cell memory generation / Andrew D. Weinberg -- The role of precursor frequency in the differentiation of memory T cells: memory by numbers / Amanda L. Marzo, Ryan T. Sowell and Bernadette Scott -- CD8 T-cell memory differentiation during acute and chronic viral infections / Vandana Kalia, Surojit Sarkar and Rafi Ahmed -- Longevity of T-cell memory following acute viral infection / Joshua M. Walker and Mark K. Slifka -- Principles of memory CD8 T-cells generation in relation to protective immunity / Maurizio Zanetti, Paola Castiglioni and Elizabeth Ingulli
,
Memory T cells in rhesus macaques / Monica Vaccari and Genoveffa Franchini -- Memory T-cell subsets in parasitic infections / Sara Colpitts and Phillip Scott -- Antigen specific memory T cells and their putative need for the generation of sustained anti-tumor responses / Kory L. Alderson and William J. Murphy -- Memory T-cell responses and survival in human cancer: remember to stay alive / Matthieu Camus and Jerome Galon -- Analysis of vaccine-induced T cells in humans with cancer / Stefanie L. Slezak ... [et al.] -- Memory T-cell homeostasis and senescence during aging / Sian M. Henson and Arne N. Akbar.
,
Electronic reproduction; Available via World Wide Web
Additional Edition:
ISBN 9781441964502
Language:
English
DOI:
10.1007/978-1-4419-6451-9
URL:
Volltext
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