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  • 1
    UID:
    (DE-627)1805909223
    Format: 1 Online-Ressource (viii, 164 pages) , illustrations
    ISBN: 0585440565 , 9780585440569
    Series Statement: Contributions to microbiology vol. 7
    Content: In the past decades, the public has been forced to revise its perception of the apparent triumph of modern hygiene and medical microbiology over infectious diseases. Not only have older infections reemerged but new epidemics, like AIDS, have lead to public uncertainty. With the onset of the bovine spongiform encephalopathy epidemic in Great Britain, novel infectious agents came into the public spotlight, ones that do not cause classical inflammation but a slow and irreversible degeneration of the central nervous system. Sensational from a scientific point of view, these agents, called proteinaceous infectious organisms or prions, were shown to be self-replicating without nucleic acid sequences to encode genomic information.In this volume, leading scientists deal with the medical, scientific and public health questions that prion infections raise. Besides the 'prion or virus' discussion, the structures of prions and their molecular biological analysis as well as the questions of strain variations and species barrier are presented. The etiological, clinical and diagnostic aspects of transmissible spongiform encephalopathies are given special attention. The epidemiology of human and animal prion diseases, disease management and possibilities for inactivation of prions are discussed from a public health perspective. Directed at scientists, physicians and the public health sector, the monograph uses a multidisciplinary approach to present the latest findings on prion infection
    Note: Includes bibliographical references and indexes
    Additional Edition: 9783318006223
    Additional Edition: 331800622X
    Additional Edition: 3805571240
    Additional Edition: Erscheint auch als Druck-Ausgabe Prions Basel ; New York : Karger, ©2001
    Language: English
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