Umfang:
Online-Ressource
ISSN:
1862-6319
Inhalt:
Abstract: This article reviews the current state‐of‐the art of diamond‐based DNA sensors. Some general concepts involved in biosensors are introduced and applied to DNA sensors. The properties of chemically vapor deposited (CVD) diamond relevant for this application are summed up, with special attention for the stability and bio‐compatibility of the material. Several routes to functionalize the diamond surface are considered. The physical properties of the obtained DNA layers are discussed in terms of surface density and molecular conformation. Possible read‐out strategies are evaluated, including optical and electronic sensing. With diamond‐based DNA sensors, real‐time and label‐free sensing is achieved. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
In:
volume:206
In:
number:3
In:
year:2009
In:
pages:391-408
In:
extent:18
In:
Physica status solidi / A. A, Applied research, Weinheim : Wiley-VCH, 1970-, 206, Heft 3 (2009), 391-408 (gesamt 18), 1862-6319
Sprache:
Englisch
DOI:
10.1002/pssa.200880486
URN:
urn:nbn:de:101:1-2023060407412030903507
URL:
https://doi.org/10.1002/pssa.200880486
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2023060407412030903507
URL:
https://d-nb.info/1291942890/34
URL:
https://doi.org/10.1002/pssa.200880486
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