Kooperativer Bibliotheksverbund

UID:

Format: 1 online resource (XVII, 341 p. 113 illus., 10 illus. in color.)

Edition: 1st ed. 2013.

ISBN: 1-62703-173-1

Series Statement: Neuromethods, 75

Content: Since its first application, microdialysis has become incredibly popular to study brain function and has been applied with success in different fields from psychopharmacology, neurobiology, and physiology in animals and also humans. Microdialysis Techniques in Neuroscience focuses on the practical aspects of microdialysis in animal and human, highlighting current technical limitations and providing a vision of what is yet to come for the determination of the most disparate compounds in the brain. The book’s contents range from new techniques for detection and quantifying the release of several different neurotransmitters in vitro and in vivo, even in freely moving animals, to sophisticated use of reverse dialysis and the application of microdialysis in pharmacokinetic studies. Each of the sixteen chapters, in fitting with the spirit of the Neuromethods series, contain an introduction that gives a broad overview of a focused topic, followed by an extensive protocol on how the experiments are performed along with invaluable practical advice.   Detailed and authoritative, Microdialysis Techniques in Neuroscience will be a valuable reference for students, neuroscientists, and physicians for the use of microdialysis in the study of brain functions and its clinical applications.

Note: Bibliographic Level Mode of Issuance: Monograph , Cerebral Microdialysis: Research Technique or Clinical Tool? -- In Vivo Microdialysis to Study Striatal Dopaminergic Neurodegeneration -- Application of Reverse Microdialysis in Neuropharmacological Studies -- Microdialysis and Advances for Sampling Synaptic and Extrasynaptic Pools -- In Vivo Microdialysis for Measurement of Oxidative Metabolism in the Living Brain -- Quantitative In Vivo Microdialysis in Pharmacokinetic Studies -- Combination of In Vivo Microdialysis with Selective Electrochemical Detection for Online Continuously Monitoring Brain Chemistry -- Application of Spinal Microdialysis in Freely Moving Rats -- Monitoring Extracellular Monoamines with In Vivo Microdialysis in Awake Rats: A Practical Approach -- Intracerebral Human Microdialysis in Parkinson’s Disease -- Monitoring Extracellular Amino Acid Neurotransmitters and hROS by In Vivo Microdialysis in Rats: A Practical Approach -- Measurement of Neuropeptides in Dialysate by LC-MS -- Achieving High Temporal Resolution for In Vivo Measurements by Microdialysis -- Indirect Analysis of Nitric Oxide and Quantitation of Selective Nitric Oxide Synthase Inhibitors in Microdialysate Samples -- Determination of Histamine in Microdialysis Samples from the Rodent Brain by Column Liquid Chromatography -- Intracerebral Microdialysis in the Study of Limbic Seizure Mechanisms and Antiepileptic Drug Action Using Freely Moving Rats. , English

Additional Edition: ISBN 1-62703-172-3

Language: English

DOI: 10.1007/978-1-62703-173-8

UID:

Format: 1 Online-Ressource (X, 282 p. 28 illus., 26 illus. in color)

ISBN: 9783319561707

Series Statement: The Receptors 31

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-319-56168-4

Language: English

DOI: 10.1007/978-3-319-56170-7

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (XVII, 501 p. 70 illus., 58 illus. in color)

ISBN: 9783319601748

Series Statement: The Receptors 33

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-319-60172-4

Language: English

DOI: 10.1007/978-3-319-60174-8

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (XII, 446 p. 69 illus., 23 illus. in color)

ISBN: 9783319704746

Series Statement: The Receptors 32

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-319-70472-2

Language: English

DOI: 10.1007/978-3-319-70474-6

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 60 S. , zahlr. Ill.

Language: Italian

Keywords: Villa Romana del Casale ; Mosaik

UID:

Format: XV, 665 S. , Ill., graph. Darst.

Edition: 1st ed.

ISBN: 9780444532350

Series Statement: Progress in brain research 172

Note: Literaturangaben

Language: English

Keywords: Serotonin ; Dopamin ; Wechselwirkung ; Serotonin ; Dopamin ; Neurochemie ; Aufsatzsammlung

URL: Inhaltsverzeichnis

URL: Verlagsangaben

URL: http://digitool.hbz-nrw.de:1801/webclient/DeliveryManager?pid=2624405&custom_att_2=simple_viewer

UID:

Format: XI, 369 Seiten , Ill., graph. Darst.

ISBN: 9783211926598

Series Statement: Journal of neutral transmission: Supplement 73

Note: Text engl.

Language: English

Keywords: Parkinson-Krankheit ; Dopaminrezeptor

UID:

Format: 1 online resource (295 p.)

Edition: 1st ed.

ISBN: 1-62081-344-0

Series Statement: Substance abuse assessment, interventions and treatment

Note: Description based upon print version of record. , Intro -- Contents -- Preface -- Chapter 1 -- Nicotine Addiction and Treatment: Recent Advances -- Abstract -- Introduction -- Nicotine Addiction -- Involvement of Nicotinic Acetylcholine Receptors -- Involvement of Neurotransmitters -- Dopamine -- Glutamate -- GABA -- Endocanabinoid System -- Endogenous Opioid System -- 5-HT -- Norepinephrine -- Involvement of Monoamine Oxidase -- Neuronal Function -- Health Effects -- Prevention -- Therapeutic Option -- Nicotine Therapy -- Non-Nicotine Therapy -- Bupropion -- Varenicline -- Nicotine Vaccine -- Research Advances -- Conclusion -- Acknowledgment -- References -- Chapter 2 -- Serotonin-Dopamine Interaction in Nicotine Addiction: Focus on 5-HT2C Receptors -- Abstract -- Introduction -- Dopamine Systems -- Serotonin Systems -- 5-HT Receptors Localization -- The 5-HT2 Receptor Family -- Effects of Nicotine on Central Dopaminergic Function -- Effects of Nicotine on Central Serotonergic Function -- Serotonin 2C (5-HT2C) and Nicotine Rewarding Properties -- Serotonergic Drug Treatment for Smoking Cessation -- Conclusion -- Acknowledgments -- References -- Chapter 3 -- Defining the Role of the Hippocampus in Nicotine Addiction -- Abstract -- Introduction -- Canonical View of Reward and Addiction -- Connectivity between the Hippocampus and the Reward Circuitry -- Nicotine-Associated Contexts and Cues -- Hippocampal Nicotinic Acetylcholine Receptors, Plasticity and Addiction -- Hippocampus, Stress and Withdrawal -- Towards a Hippocampus Model for Nicotine Addiction -- Acknowledgments -- References -- Chapter 4 -- Nicotine, Neurodegeneration, and Neuroprotection in Neuropsychiatric Disorders -- Abstract -- Introduction -- Nicotine Neuroprotection -- in Neurodegenerative Diseases -- Nicotine and Alzheimer's Disease -- Nicotine Influence on Cognitive Impairment. , Nicotine, the Cholinergic System and Alzheimer's Disease -- Nicotine and Parkinson's Disease -- Nicotine and the Pathology of Parkinson's Disease -- Nicotine and other Memory Disorders -- Nicotine Neuroprotection in Neural Injury -- Nicotine Neuroprotection in Psychiatric Disorders -- Nicotine and Schizophrenia -- Nicotinic Acetylcholine Receptors in Schizophrenia -- Auditory Evoked Potential Inhibition Deficits in Schizophrenia -- Smooth Pursuit Eye Movement Deficits in Schizophrenia -- Prepulse Inhibition of Startle Response Deficits in Schizophrenia -- Neuropsychological Impairments in Schizophrenia -- Pharmacologic Interventions Targeting the Nicotinic Acetylcholine System -- Nicotine and Bipolar Mood Disorder -- Symptom Progression in Smoking Bipolar Patients -- Genetics of Bipolar Disorder and Nicotinic Acetylcholine Receptors -- Conclusion -- References -- Chapter 5 -- Stress as a Risk Factor for Transition to Heightened Nicotine Intake: Evidence from a Rat Model of Nicotine Self-Administration -- Abstract -- Introduction -- Materials and Methods -- Subjects -- Self-Administration Apparatus -- Food Training -- Surgery -- Nicotine Self-Administration -- Effect of Pharmacological Stress on Nicotine Intake -- Statistical Analyses -- Results -- Nicotine Self-Administration in the LNT and HNT Rats -- Effect of Yohimbine on Nicotine Self-Administration in the LNT Rats -- Effect of Yohimbine on Nicotine Self-Administration in the HNT Rats -- Effect of Yohimbine in Saline-Trained Rats -- Discussion -- Conclusion -- Acknowledgments -- References -- Chapter 6 -- Smoking, Nicotine and Depression: A Review -- Abstract -- Introduction -- General Aspects of Nicotine -- Pharmacology -- Metabolism -- Nicotinic Receptors -- General Characteristics of Depression -- Smoking, Nicotine and Depression -- Epidemiology. , Hypothesis on the Increase in Indexes of Smoking among Patients with Major Depression -- Interaction Mechanisms of Nicotine in Depressive Disorders -- Conclusion -- References -- Chapter 7 -- New Psychological Approaches in Nicotine Addiction -- Abstract -- Introduction -- Prevention -- Cessation -- Relapse Prevention -- Conclusion -- References -- Chapter 8 -- Cognitive Consequences of Adolescent and Adult Nicotine Exposure: Utility of Animal Models -- Abstract -- Introduction -- Benefits of Rat Models for Studying Developmental Processes in Drug Addiction -- The Utility of the Rat as an Experimental Model of Adolescent Nicotine Exposure -- Hallmarks of Adolescence in the Rat -- Effects of Adult Nicotine Exposure on Cognition in Animals -- Effects of Adolescent Nicotine Exposure on Neural Development and Cognition in Animals -- Conclusion -- Acknowledgments -- References -- Chapter 9 -- Psychosocial Risk Factors for Smoking and Nicotine Dependence: Implications for Prevention and Treatment -- Abstract -- Introduction -- Purpose of Study -- Background -- Properties and Effects of Nicotine -- Mechanism of Nicotine Dependence -- Theoretical Framework -- Neurobiological Model -- Associative Learning Model -- Depression -- Smoking Expectancies -- The Personality Trait of Neuroticism -- Childhood Adversity -- Methodology of the Study -- Sample -- Measures -- Data Collection -- Results -- Conclusion -- Implications for Treatment: Assessment -- Nicotine Replacement Therapy -- Anti-Depressant Therapy -- Varencline -- Strategies to Motivate Change and Prevent Relapse -- Case Study -- Further Recommendations -- References -- Chapter 10 -- Effects Associated with the Structure of Adsorbents on the Degrees to Which Nicotine, Tar and CO are Reduced in Tobacco Smoke -- Abstract -- Introduction. , Novel Materials Efficient For Reducing Nicotine, Tar and CO Contents -- Preparation of Cigarette Samples -- Composite Filter -- Chemical Composition of the Mainstream Tobacco Smoke -- Efficiency of the Sorption Removal -- The Factor of Selectivity -- Specific Sorption Capacity of Investigated Material -- The Effects of a Hydrophilic Type Zeolite on the Degree of Reduction of Nicotine, Tar and CO in Tobacco Smoke -- The Effects Associated with the Degree of Hydrophobicity of the Zeolite on the Degree of Reduction of Tobacco Smoke Components -- The Effects Associated With the Type of Amorphous Material on the Degree of Reduction of Tobacco Smoke Components -- Conclusion -- Acknowledgment -- References -- Chapter 11 -- Kinetics of Nicotine Bonding Onto and Release from Poly (Acrylic -co-Methacrylic Acid) Hydrogel -- Abstract -- Introduction -- Poly(Acrylic Acid-Cco-Methacrylic Acid) Hydrogel Synthesis -- Nicotine Bonding and Release -- Poly(Acrylic Acid-co-methacrylic Acid) Hydrogel Synthesis -- Nicotine Bonding -- Nicotine Release -- Isothermal Kinetics of Nicotine Bonding and Release -- Models of Kinetic Nicotine Bonding to the Hydrogel -- The Kinetics Model of Nicotine Release from the Hydrogel -- Conclusion -- Acknowledgment -- References -- Index -- Blank Page. , English

Additional Edition: ISBN 1-62081-290-8

Language: English

UID:

Format: 1 Online-Ressource (XVII, 501 p. 70 illus., 58 illus. in color).

ISBN: 978-3-319-60174-8

Series Statement: The Receptors 33

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-319-60172-4

Language: English

DOI: 10.1007/978-3-319-60174-8

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Format: 1 Online-Ressource (X, 282 p. 28 illus., 26 illus. in color).

ISBN: 978-3-319-56170-7

Series Statement: The Receptors 31

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-319-56168-4

Language: English

DOI: 10.1007/978-3-319-56170-7

URL: Volltext  (URL des Erstveröffentlichers)